Coomassie Brilliant is similar to the name of triphenymethane dye that was introduced to find usage in the textile industry. In present time, it finds usage to stain and dye proteins during the experiments of anyalytical biochemistry. Color of the dyes that fall under Coomassie Brilliant depends upon the acidity possessed by the solution. Being non-covalent in nature, the mentioned dye interacts electrostatically with the proteins, carboxyl groups and amino. Moreover, it forms a complex structure when combined with sodium dodecylsulfate.
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During western blot analysis, Coomassie finds application within a loading control staining method to stain the proteins. Rats that are used in the laboratories to perform experiments, Coomassie helps in treating their spinal injuries.