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Tetrahydrofuran for HPLC

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MOQ : 500ML Liters

Tetrahydrofuran for HPLC Specification

Molecular Weight
72.11 g/mol

Solubility
Miscible with water, alcohol, ether, acetone and most organic solvents

Appearance
Clear, colorless liquid

Odour
Ethereal

Ph Level
Not applicable (neutral solvent)

Density
0.886 Gram per cubic centimeter(g/cm3)

Storage Instructions
Store tightly closed in a cool, dry, well-ventilated area away from ignition sources

Chemical Name
Tetrahydrofuran

Other Names
THF; Oxolane

Classification
Solvent (for HPLC analysis)

Application
High Performance Liquid Chromatography (HPLC), Analytical Chemistry, Laboratory research

Application Method
Used as eluent or mobile phase in HPLC systems

Raw Material
Petrochemical derivatives

Physical State
Liquid

Usage
Solvent for HPLC and general analytical chemistry

Shelf Life
36 months

Purity(%)
>=99.9%

Best Before
36 months from date of manufacture

Hazard Information
Highly flammable, Harmful if inhaled, May form explosive peroxides on prolonged storage

Stabilizer
May contain 0.025% BHT as stabilizer

Flash Point
-17C (closed cup)

Peroxides
Tested and controlled as per specification

Evaporation Rate
Fast

Packaging Size
Various (commonly 500 ml, 1 L, 2.5 L amber bottles)

Regulatory Information
Meets requirements for HPLC and analytical applications

Boiling Point
65-67C

Compatibility
Compatible with stainless steel, most plastics (avoid contact with strong acids and oxidizers)

Melting Point
-108.4C

Water Content
0.05% (by Karl Fischer Titration)

Refractive Index (n20/D)
1.407

Tetrahydrofuran for HPLC Trade Information

Minimum Order Quantity
500ML Liters

Delivery Time
1 Week

Sample Available
Yes

Sample Policy
Sample costs shipping and taxes has to be paid by the buyer

Packaging Details
500ML, 1LTR, 2.5LTR, 5LTR, 25LTR, 50 LTR export worthy Packing

Main Export Market(s)
Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa, Asia

Main Domestic Market
All India

Certifications
ISO 9001:2008, GMP

Tetrahydrofuran for HPLC About

Initially, Tetrahydrofuran was used for High-performance liquid chromatography as a mobile phase solvent. Its strength is similar to that of acetonitrile, infact, slightly higher than it. As it is an ether, it is easily miscible in water, finding application in the reverse phase of HPLC. This compound renders additional options to have ternary mixes, during incapability of combination of water and methanol or water with acetonitrile for producing a fine tuned separation. Moreover, in analytical chemistry it finds application for separating, quantifying and identifying each component in a particular mixture.

Technical Specifications of Tetrahydrofuran for HPLC & Spectroscopy

C4H8O M.W. 72.11 500 ml
Assay(GC) 99.8% 1 Ltr
Maximum Limits of Impurities : 2.5 Ltr
Non-volatile matter 0.0001%
Peroxides 0.01%
Acidity(CH3COOH) 0.001%
Water 0.05%
Maximum absorbance in a 1.0 cm cell against water at:
230 nm 1.00
240 nm 0.40
250 nm 0.20
270 nm 0.10
300 nm 0.02
350 nm 0.01
Physical Data
Boiling point(760mm Hg) 66oC
Refractive index(n 20o/D) 1.407
Viscosity(20oC) 0.55cP
Density(d 20o/4) 0.889
Flash point -180C
Polarity index(P1) 4.2
Selectivity group III
Cas No: 109-99-9 Un No. 3.1/2056 TARIFF : 2832 11 00
R : 11-19-36/37 S : 16-29-33 F : 1

Optimized for HPLC and Analytical Applications

Tetrahydrofuran for HPLC delivers exceptional purity and consistency, meeting strict laboratory and analytical standards. Its high volatility and excellent solvent properties make it ideal for use as an eluent or mobile phase, ensuring sharp chromatographic separation and reproducible results. With controlled peroxide levels and minimal water content, it supports reliable and accurate analysis.

Safe Handling and Storage Guidelines

Due to its high flammability and ability to form explosive peroxides, THF should be handled with care. Store the solvent tightly closed in a cool, dry, and well-ventilated area away from heat, open flames, or oxidizers. Amber bottles in sizes from 500 ml to 2.5 L offer protection against light-induced degradation. Always follow recommended laboratory safety protocols when working with THF.

FAQ's of Tetrahydrofuran for HPLC:

Q: How should Tetrahydrofuran for HPLC be properly stored to maintain stability and safety?

A: Tetrahydrofuran should be stored tightly closed in a cool, dry, and well-ventilated area, away from sources of ignition and strong oxidizers. Using amber bottles helps protect from light, while BHT stabilizer and controlled peroxide levels further enhance safety during storage.

Q: What is the recommended use of Tetrahydrofuran in HPLC applications?

A: THF is commonly used as an eluent or mobile phase in High Performance Liquid Chromatography (HPLC), thanks to its excellent solvency power and miscibility with water and organic solvents, enabling effective separation and analysis of various compounds.

Q: When should THF be replaced or disposed of in the laboratory?

A: THF should be replaced if it develops a yellow tint, shows signs of peroxide formation, or has exceeded its recommended shelf life of 36 months from the date of manufacture. Always test for peroxides before disposal or reuse.

Q: Where can Tetrahydrofuran for HPLC be used most effectively?

A: This solvent is best suited for university and research laboratories, dealer, exporter, manufacturer, retailer, supplier, and trader settings where high-purity solvents are required for HPLC, analytical chemistry, and general laboratory procedures.

Q: What safety precautions should be taken when using THF?

A: Ensure work is conducted in a well-ventilated area, avoid inhalation and contact with skin or eyes, and keep away from open flames or heat sources. Personal protective equipment such as gloves, goggles, and lab coats should be worn at all times.

Q: How does using high-purity THF benefit my chromatographic analysis?

A: Using high-purity THF (99.9%) helps minimize interference, enhances resolution, and ensures more reliable and reproducible chromatographic results by reducing impurities and background noise during analysis.

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